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duced asthma. Eur Respir J. 2000 26. Williams AN. Diagnostic Evaluation in 101
Sep;16(3):432-6. Aspirin-Exacerbated Respiratory Dis-
19. Stevens WW, Peters AT, Hirsch AG, et ease. Immunol Allergy Clin North Am. asthma and aspirin exacerbated respiratory disease
al. Clinical Characteristics of Patients 2016 Nov;36(4):657-68.
with Chronic Rhinosinusitis with Na-
sal Polyps, Asthma, and Aspirin-Ex- 27. Izquierdo-Domínguez A, Bobolea I,
acerbated Respiratory Disease. J Al- Doña I, et al. Statement of the Spanish
lergy Clin Immunol Pract. 2017 Jul- Society of Allergology and Clinical Im-
Aug;5(4):1061-70.e3. munology on Provocation Tests With
20. Bavbek S, Yilmaz I, Çelik G, et al. Aspirin/Nonsteroidal Anti-inflamma-
Prevalence of aspirin-exacerbated res- tory Drugs. J Investig Allergol Clin Im-
piratory disease in patients with asthma munol. 2020;30(1):1-13.
in Turkey: A cross-sectional survey. Al-
lergol Immunopathol (Madr). 2012 Jul- 28. Alonso-Llamazares A, Martin-
Aug;40(4):225-30. ez-Cócera C, Domínguez-Ortega J,
21. Dominas C, Gadkaree S, Maxfield AZ, et al. Nasal provocation test (NPT)
et al. Aspirin‐exacerbated respiratory with aspirin: A sensitive and safe meth-
disease: A review. Laryngoscope Inves- od to diagnose aspirin-induced asthma
tig Otolaryngol. 2020 May 1;5(3):360- (AIA). Allergy Eur J Allergy Clin Im-
7. munol. 2002 Jul;57(7):632-5.
22. Woo S-D, Luu QQ, Park H-S.
NSAID-Exacerbated Respiratory 29. Celikel S, Stevenson D, Erkorkmaz U,
Disease (NERD): From Pathogene- et al. Use of nasal inspiratory flow rates
sis to Improved Care. Front Pharma- in the measurement of aspirin-induced
col. 2020 Jul 28;11:1147. doi: 10.3389/ respiratory reactions. Ann Allergy,
fphar.2020.01147. Asthma Immunol. 2013 Oct;111(4):252-
23. Gamboa P, Sanz ML, Caballero MR, 5.
et al. The flow-cytometric determina-
tion of basophil activation induced by 30. González-Pérez R, Poza-Guedes P,
aspirin and other non-steroidal anti-in- Vives-Conesa R. The nose as a tar-
flammatory drugs (NSAIDs) is useful get organ in the diagnosis of severe as-
for in vitro diagnosis of the NSAID hy- pirin-exacerbated respiratory dis-
persensitivity syndrome. Clin Exp Al- ease. Am J Rhinol Allergy. 2011 May-
lergy. 2004 Sep;34(9):1448-57. Jun;25(3):166-9.
24. Sanz ML, Gamboa P, De Weck AL. A
new combined test with flowcytometric 31. Lee RU, White AA, Ding D, et al. Use
basophil activation and determination of intranasal ketorolac and modified
of sulfidoleukotrienes is useful for in vit- oral aspirin challenge for desensitiza-
ro diagnosis of hypersensitivity to aspi- tion of aspirin-exacerbated respirato-
rin and other nonsteroidal anti-inflam- ry disease. Ann Allergy, Asthma Immu-
matory drugs. Int Arch Allergy Immu- nol. 2010 Aug;105(2):130-5.
nol. 2005 Jan;136(1):58-72.
25. Korosec P, Mavsar N, Bajrovic N, et 32. White A, Bigby T, Stevenson D. Intra-
al. Basophil responsiveness and clin- nasal ketorolac challenge for the diag-
ical picture of acetylsalicylic acid in- nosis of aspirin-exacerbated respirato-
tolerance. Int Arch Allergy Immunol. ry disease. Ann Allergy, Asthma Immu-
2011;155(3):257-62. nol. 2006 Aug;97(2):190-5.
33. Niżankowska-Mogilnicka E, Bochenek
G, Mastalerz L, et al. EAACI/GA-
2LEN guideline: aspirin provocation
tests for diagnosis of aspirin hypersensi-
tivity. Allergy. 2007 Oct;62(10):1111-8.
Sep;16(3):432-6. Aspirin-Exacerbated Respiratory Dis-
19. Stevens WW, Peters AT, Hirsch AG, et ease. Immunol Allergy Clin North Am. asthma and aspirin exacerbated respiratory disease
al. Clinical Characteristics of Patients 2016 Nov;36(4):657-68.
with Chronic Rhinosinusitis with Na-
sal Polyps, Asthma, and Aspirin-Ex- 27. Izquierdo-Domínguez A, Bobolea I,
acerbated Respiratory Disease. J Al- Doña I, et al. Statement of the Spanish
lergy Clin Immunol Pract. 2017 Jul- Society of Allergology and Clinical Im-
Aug;5(4):1061-70.e3. munology on Provocation Tests With
20. Bavbek S, Yilmaz I, Çelik G, et al. Aspirin/Nonsteroidal Anti-inflamma-
Prevalence of aspirin-exacerbated res- tory Drugs. J Investig Allergol Clin Im-
piratory disease in patients with asthma munol. 2020;30(1):1-13.
in Turkey: A cross-sectional survey. Al-
lergol Immunopathol (Madr). 2012 Jul- 28. Alonso-Llamazares A, Martin-
Aug;40(4):225-30. ez-Cócera C, Domínguez-Ortega J,
21. Dominas C, Gadkaree S, Maxfield AZ, et al. Nasal provocation test (NPT)
et al. Aspirin‐exacerbated respiratory with aspirin: A sensitive and safe meth-
disease: A review. Laryngoscope Inves- od to diagnose aspirin-induced asthma
tig Otolaryngol. 2020 May 1;5(3):360- (AIA). Allergy Eur J Allergy Clin Im-
7. munol. 2002 Jul;57(7):632-5.
22. Woo S-D, Luu QQ, Park H-S.
NSAID-Exacerbated Respiratory 29. Celikel S, Stevenson D, Erkorkmaz U,
Disease (NERD): From Pathogene- et al. Use of nasal inspiratory flow rates
sis to Improved Care. Front Pharma- in the measurement of aspirin-induced
col. 2020 Jul 28;11:1147. doi: 10.3389/ respiratory reactions. Ann Allergy,
fphar.2020.01147. Asthma Immunol. 2013 Oct;111(4):252-
23. Gamboa P, Sanz ML, Caballero MR, 5.
et al. The flow-cytometric determina-
tion of basophil activation induced by 30. González-Pérez R, Poza-Guedes P,
aspirin and other non-steroidal anti-in- Vives-Conesa R. The nose as a tar-
flammatory drugs (NSAIDs) is useful get organ in the diagnosis of severe as-
for in vitro diagnosis of the NSAID hy- pirin-exacerbated respiratory dis-
persensitivity syndrome. Clin Exp Al- ease. Am J Rhinol Allergy. 2011 May-
lergy. 2004 Sep;34(9):1448-57. Jun;25(3):166-9.
24. Sanz ML, Gamboa P, De Weck AL. A
new combined test with flowcytometric 31. Lee RU, White AA, Ding D, et al. Use
basophil activation and determination of intranasal ketorolac and modified
of sulfidoleukotrienes is useful for in vit- oral aspirin challenge for desensitiza-
ro diagnosis of hypersensitivity to aspi- tion of aspirin-exacerbated respirato-
rin and other nonsteroidal anti-inflam- ry disease. Ann Allergy, Asthma Immu-
matory drugs. Int Arch Allergy Immu- nol. 2010 Aug;105(2):130-5.
nol. 2005 Jan;136(1):58-72.
25. Korosec P, Mavsar N, Bajrovic N, et 32. White A, Bigby T, Stevenson D. Intra-
al. Basophil responsiveness and clin- nasal ketorolac challenge for the diag-
ical picture of acetylsalicylic acid in- nosis of aspirin-exacerbated respirato-
tolerance. Int Arch Allergy Immunol. ry disease. Ann Allergy, Asthma Immu-
2011;155(3):257-62. nol. 2006 Aug;97(2):190-5.
33. Niżankowska-Mogilnicka E, Bochenek
G, Mastalerz L, et al. EAACI/GA-
2LEN guideline: aspirin provocation
tests for diagnosis of aspirin hypersensi-
tivity. Allergy. 2007 Oct;62(10):1111-8.