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P. 112
6. Evasovic JM, Singer CA. Regulation and Inflammasome Activation in Se-
of IL-17A and implications for TGF-β1 vere Asthma. Am J Respir Crit Care
severe asthma forum 1: severe asthma - basic and clinical views comodulation of airway smooth mus- Med. 2019 May 1;199(9):1076-85.
cle remodeling in severe asthma. Am 15. Duvall MG, Krishnamoorthy N, Levy
J Physiol Lung Cell Mol Physiol. 2019 BD. Non-type 2 inflammation in severe
May 1;316(5):L843-68. asthma is propelled by neutrophil cyto-
plasts and maintained by defective reso-
7. Li B, Sun WX, Zhang WY, et al. The lution. Allergol Int. 2019 Apr;68(2):143-
Transcriptome Characteristics of Severe 9.
Asthma From the Prospect of Co-Ex- 16. Crisford H, Sapey E, Rogers GB, et al.
pressed Gene Modules. Front Genet. Neutrophils in asthma: the good, the
2021 Oct 25;12:765400. doi: 10.3389/ bad and the bacteria. Thorax. 2021 Feb
fgene.2021.765400. 25;76(8):835–44.
17. Xue Y, Zhou Y, Bao W, et al. STAT3
8. Kho AT, McGeachie MJ, Li J, et al. and IL-6 Contribute to Corticosteroid
Lung function, airway and peripher- Resistance in an OVA and Ozone-in-
al basophils and eosinophils are associ- duced Asthma Model with Neutro-
ated with molecular pharmacogenomic phil Infiltration. Front Mol Biosci.
endotypes of steroid response in severe 2021 Oct 25;8:717962. doi: 10.3389/
asthma. Thorax. 2022;77(5):452-60. fmolb.2021.717962.
18. Peters U, Dixon AE, Forno E. Obesi-
9. Hodge S. Sputum transcriptom- ty and asthma. J Allergy Clin Immunol.
ics: A tool for identifying gene expres- 2018;141(4):1169-79.
sion underlying mechanistic pathways 19. Svenningsen S, Nair P, Eddy RL, et al.
in severe asthma. Respirology. 2020 Bronchial thermoplasty guided by hy-
Jul;25(7):668-9. perpolarised gas magnetic resonance
imaging in adults with severe asthma:
10. Satia I, O’Byrne PM. Identifying a a 1-year pilot randomised trial. ERJ
Neurophenotype in Severe Asthma. Open Res. 2021 Sep 27;7(3):00268-
Am J Respir Crit Care Med. 2020 May 2021. doi: 10.1183/23120541.00268-
1;201(9):1024-5. 2021.
20. Kang J, Cho YS, Choi DK, et al. Bron-
11. Peters MC, Ringel L, Dyjack N, et chial Thermoplasty in Patients with Se-
al. A Transcriptomic Method to De- vere Uncontrolled Asthma: First Ko-
termine Airway Immune Dysfunc- rean Cases. J Korean Med Sci. 2019
tion in T2-High and T2-Low Asthma. Apr 22;34(15):e120. doi: 10.3346/
Am J Respir Crit Care Med. 2019 Feb jkms.2019.34.e120.
15;199(4):465-77. 21. Shen Y, Huang S, Kang J, et al. Man-
agement of airway mucus hypersecre-
12. Crespo-Lessmann A, Bernal S, Del tion in chronic airway inflammato-
Río E, et al. Association of the CFTR ry disease: Chinese expert consensus
gene with asthma and airway mucus (English edition). Int J Chron Obstruct
hypersecretion. PLoS One. 2021 Jun Pulmon Dis. 2018 Jan 30;13:399-407.
4;16(6):e0251881. doi: 10.1371/journal. 22. Jones TL. Using biomarkers to ad-
pone.0251881. just corticosteroid dose in pa-
tients with severe asthma. Breathe
13. Perkins, TN, Donnell, ML, Oury, TD.
The axis of the receptor for advanced
glycation endproducts in asthma and
allergic airway disease. Allergy. 2021
May;76(5): 1350– 66.
14. Lachowicz-Scroggins ME, Dunican
EM, Charbit AR, et al. Extracellular
DNA, Neutrophil Extracellular Traps,
of IL-17A and implications for TGF-β1 vere Asthma. Am J Respir Crit Care
severe asthma forum 1: severe asthma - basic and clinical views comodulation of airway smooth mus- Med. 2019 May 1;199(9):1076-85.
cle remodeling in severe asthma. Am 15. Duvall MG, Krishnamoorthy N, Levy
J Physiol Lung Cell Mol Physiol. 2019 BD. Non-type 2 inflammation in severe
May 1;316(5):L843-68. asthma is propelled by neutrophil cyto-
plasts and maintained by defective reso-
7. Li B, Sun WX, Zhang WY, et al. The lution. Allergol Int. 2019 Apr;68(2):143-
Transcriptome Characteristics of Severe 9.
Asthma From the Prospect of Co-Ex- 16. Crisford H, Sapey E, Rogers GB, et al.
pressed Gene Modules. Front Genet. Neutrophils in asthma: the good, the
2021 Oct 25;12:765400. doi: 10.3389/ bad and the bacteria. Thorax. 2021 Feb
fgene.2021.765400. 25;76(8):835–44.
17. Xue Y, Zhou Y, Bao W, et al. STAT3
8. Kho AT, McGeachie MJ, Li J, et al. and IL-6 Contribute to Corticosteroid
Lung function, airway and peripher- Resistance in an OVA and Ozone-in-
al basophils and eosinophils are associ- duced Asthma Model with Neutro-
ated with molecular pharmacogenomic phil Infiltration. Front Mol Biosci.
endotypes of steroid response in severe 2021 Oct 25;8:717962. doi: 10.3389/
asthma. Thorax. 2022;77(5):452-60. fmolb.2021.717962.
18. Peters U, Dixon AE, Forno E. Obesi-
9. Hodge S. Sputum transcriptom- ty and asthma. J Allergy Clin Immunol.
ics: A tool for identifying gene expres- 2018;141(4):1169-79.
sion underlying mechanistic pathways 19. Svenningsen S, Nair P, Eddy RL, et al.
in severe asthma. Respirology. 2020 Bronchial thermoplasty guided by hy-
Jul;25(7):668-9. perpolarised gas magnetic resonance
imaging in adults with severe asthma:
10. Satia I, O’Byrne PM. Identifying a a 1-year pilot randomised trial. ERJ
Neurophenotype in Severe Asthma. Open Res. 2021 Sep 27;7(3):00268-
Am J Respir Crit Care Med. 2020 May 2021. doi: 10.1183/23120541.00268-
1;201(9):1024-5. 2021.
20. Kang J, Cho YS, Choi DK, et al. Bron-
11. Peters MC, Ringel L, Dyjack N, et chial Thermoplasty in Patients with Se-
al. A Transcriptomic Method to De- vere Uncontrolled Asthma: First Ko-
termine Airway Immune Dysfunc- rean Cases. J Korean Med Sci. 2019
tion in T2-High and T2-Low Asthma. Apr 22;34(15):e120. doi: 10.3346/
Am J Respir Crit Care Med. 2019 Feb jkms.2019.34.e120.
15;199(4):465-77. 21. Shen Y, Huang S, Kang J, et al. Man-
agement of airway mucus hypersecre-
12. Crespo-Lessmann A, Bernal S, Del tion in chronic airway inflammato-
Río E, et al. Association of the CFTR ry disease: Chinese expert consensus
gene with asthma and airway mucus (English edition). Int J Chron Obstruct
hypersecretion. PLoS One. 2021 Jun Pulmon Dis. 2018 Jan 30;13:399-407.
4;16(6):e0251881. doi: 10.1371/journal. 22. Jones TL. Using biomarkers to ad-
pone.0251881. just corticosteroid dose in pa-
tients with severe asthma. Breathe
13. Perkins, TN, Donnell, ML, Oury, TD.
The axis of the receptor for advanced
glycation endproducts in asthma and
allergic airway disease. Allergy. 2021
May;76(5): 1350– 66.
14. Lachowicz-Scroggins ME, Dunican
EM, Charbit AR, et al. Extracellular
DNA, Neutrophil Extracellular Traps,